Table 4.
The change in eGFR at week 34, week 58, and at the final visit
| Overall | 2 mg | 4 mg | |||||||
|---|---|---|---|---|---|---|---|---|---|
| n | Mean ± SD | P value | n | Mean ± SD | P value | n | Mean ± SD | P value | |
| eGFR value (mL/min/1.73 m2) | |||||||||
| Baseline | 326 | 69.6 ± 13.2 | – | 276 | 69.7 ± 12.7 | – | 43 | 70.0 ± 15.7 | – |
| Week 34 | 299 | 70.1 ± 13.8 | – | 259 | 70.1 ± 13.5 | – | 40 | 70.4 ± 15.6 | – |
| Week 58 | 105 | 69.0 ± 14.2 | – | 92 | 69.0 ± 14.6 | – | 13 | 68.4 ± 10.7 | – |
| Final visit | 310 | 70.2 ± 14.3 | – | 265 | 70.4 ± 14.0 | – | 41 | 70.1 ± 15.5 | – |
| Change in eGFR (mL/min/1.73 m2) | |||||||||
| Week 34 | 299 | 0.6 ± 6.2 | 0.122 | 259 | 0.6 ± 6.0 | 0.081 | 40 | − 0.1 ± 7.3 | 0.949 |
| Week 58 | 105 | − 1.1 ± 7.8 | 0.158 | 92 | − 0.7 ± 7.8 | 0.416 | 13 | − 4.1 ± 7.7 | 0.081 |
| Final visit | 310 | 0.7 ± 6.8 | 0.089 | 265 | 0.9 ± 6.7 | 0.038* | 41 | − 0.5 ± 7.6 | 0.684 |
*P < 0.05 (vs. baseline)