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. 2019 Mar 30;38(2):392–401. doi: 10.1007/s10637-019-00758-8

Table 3.

Summary of subjects with an overall response of PR or better

Subject (Age/Sex) Tumor Type Best Response Time to Best Response (Months) Duration of SMK Therapy (Months) ECOG Score* (Baseline / End of Cycle 1) EORTC Global Health Status Score# (Baseline / End of Cycle 1)
70/Female Breast CR 1.5 4.1 2/1 5/7
50/Female Breast CR 3.3 40.9 1/0 3/7
51/Female Breast CR 3.2 14.8 2/1 3/6
57/Male Appendix CR 5.6 4.7 1/0 5/7
40/Female Breast PR 1.4 7.7 3/1 4/6
54/Female Breast PR 1.4 3.3 2/1 7/6
58/Female Lung PR 4.1 14.3 2/1 4/5
58/Male Pancreas PR 3.4 3.4 2/1 4/5
48/Female Breast PR 1.5 3.1 1/0 4/6
33/Female Thyroid PR 15.5 12.9 1/0 3/7

*A reduction in ECOG score indicates improvement. #An increase in EORTC global health status score indicates an improvement