Fig. 3.

The radiomic feature maps (RFM) obtained from single and multiparametric radiomics (mpRad) analysis in a patient with a malignant lesion. The straight yellow arrow highlights the lesion location. The curved arrow demonstrates a benign cyst in the breast. a Multiparametric MRI parameters used for the mpRad framework. b Single radiomic gray-level co-occurrence matrix (GLCM) entropy features maps from each MRI parameter. c The mpRad RFMs tissue signature co-occurrence matrix (TSCM) and tissue signature complex interaction network (TSCIN) radiomic features. Note, the improved tissue delineation between the different tissue types using the mpRad framework