Table 1.
Patient characteristics
| Characteristic | 50.4 Gy (n = 171) | 60 Gy (n = 825) | p value | ||
|---|---|---|---|---|---|
| n | % | n | % | ||
| Sex | |||||
| Male | 147 | 86.0 | 731 | 88.6 | 0.3307 |
| Female | 24 | 14.0 | 94 | 11.4 | |
| Age (years) | |||||
| Median (range) | 68 (40–86) | 69 (37–91) | 0.006 | ||
| Histology | |||||
| SCC | 161 | 94.7 | 790 | 96.5 | 0.1298 |
| AD | 6 | 3.5 | 11 | 1.3 | |
| Other | 3 | 1.8 | 18 | 2.2 | |
| Location | |||||
| Upper | 38 | 22.2 | 177 | 21.5 | 0.0133 |
| Middle | 79 | 46.2 | 468 | 56.7 | |
| Lower | 54 | 31.6 | 180 | 21.8 | |
| cT | |||||
| cTx | 0 | 0.0 | 2 | 0.2 | 0.0001 |
| cT0 | 0 | 0.0 | 0 | 0.0 | |
| cT1a | 14 | 8.2 | 34 | 4.1 | |
| cT1b | 27 | 15.8 | 173 | 21.0 | |
| cT2 | 24 | 14.0 | 96 | 11.6 | |
| cT3 | 65 | 38.0 | 242 | 29.3 | |
| cT4a | 24 | 14.0 | 83 | 10.1 | |
| cT4b | 17 | 9.9 | 195 | 23.6 | |
| cN | |||||
| cNx | 0 | 0.0 | 0 | 0.0 | 0.554 |
| cN0 | 47 | 27.5 | 269 | 32.6 | |
| cN1 | 63 | 36.8 | 274 | 33.2 | |
| cN2 | 41 | 24.0 | 199 | 24.1 | |
| cN3 | 20 | 11.7 | 83 | 10.1 | |
| cStage | |||||
| cStage I | 34 | 19.9 | 219 | 26.6 | 0.1493 |
| cStage II–III | 96 | 56.1 | 442 | 53.6 | |
| cStage IV | 41 | 24.0 | 164 | 19.9 | |
| Elective nodal irradiation | |||||
| Yes | 75 | 43.9 | 401 | 48.6 | 0.0011 |
| No | 72 | 42.1 | 375 | 45.5 | |
| Unknown | 24 | 14.0 | 49 | 5.9 | |
SCC squamous cell carcinoma, AD adenocarcinoma