Table 2.

Potential hair cell-specific biomarker proteins

Protein	Gene	Cell type	Function	Targeting	Ref
Chloride intracellular channel protein 5	CLIC5	OHC, IHC	Channel	None	[16]
Gaba receptors	GABBR1, GABBR2	OHC, IHC	Receptors	None	[17]
Large conductance voltage and calcium activated potassium (BK) channel	KCNMA1	OHC, IHC	Channel	Peptide	[18, 19]
LHFPL tetraspan subfamily member 5 protein	LHFPL5	OHC, IHC	Structural protein	None	[20, 21]
Mechanoelectrical transducer (MET) channel	Various	OHC, IHC	Channel	None	[22]
Otoferlin	OTOF	IHC	Synapse protein	None	[23]
Phospholipid-transporting ATPase IC	ATP8B1	OHC, IHC,	Transport protein	None	[24]
Prestin	SLC26A5	OHC	Motor protein	Peptide	[25–27]
Transmembrane channel-like protein 1	TMC1	OHC, IHC	Channel	None	[28, 29]
Transmembrane channel-like protein 2	TMC2	OHC, IHC	Channel	None	[28]
Vesicular glutamate transporter 3	SLC17A8	IHC, SG	Transport protein	None	[30, 31]