Table 1.
Patient and disease characteristics
| Characteristics | N = 22, n (%) |
|---|---|
| Gender | |
| Male | 13 (59%) |
| Female | 9 (41%) |
| Age, years, median (range) | 60 (41–82) |
| Race | |
| White | 19 (86%) |
| African American | 1 (5%) |
| Missing | 2 (9%) |
| ECOG | |
| 0 | 4 (18%) |
| 1 | 18 (82%) |
| Prior therapy | |
| Surgery | 14 (64%) |
| Radiotherapy | 20 (91%) |
| Prior systemic treatments | |
| 0 | 6 (27%) |
| 1 | 7 (32%) |
| ≥ 2 | 9 (41%) |
| Metastatic Disease | 22 (100%) |
| Sites of metastases | |
| Lung | 20 (91%) |
| Bone | 8 (36%) |
| Liver | 5 (23%) |
| Lymph node | 5 (23%) |
| Notch ICD IHC | |
| Positive | 14 (64%) |
| Negative | 8 (36%) |
ECOG, Eastern Cooperative Oncology Group; NICD, Notch-1 intracellular domain