Figure 1.

Distribution of absolute CD4+ T cell count history in viremic non-progressors (VNPs) and clinical, immunological, and virological characteristics of the study groups. (A) 18 VNPs were recruited following stringent criteria. The cutoff absolute count of 500 cells/mm³ is represented by the solid line. The last time point, for each sample, is the time of recruitment of participants for the study. Each line represents one individual. Individuals with <6 data points are represented as a *(n = 3). Color represents years of infection until recruitment for the study: Blue, 7–10 years; Green, 10–15 years; red, >15 years. (B,C) Absolute T cell count in blood as measured by flow cytometry. (B) Absolute CD4+ T cell count. (C) Absolute CD8+ T cell count. (D) CD4/CD8 ratio calculated from absolute CD4+ and CD8+ T cell count. (E) Plasma viral load (Log₁₀ VL). (F–I) Correlation between CD4/CD8 ratio and plasma viral load in (F) VNPs, (G) putative progressors (PuPs), (H) standard progressors (SPs), and (I) viremic controllers (VCs). Comparisons between groups were calculated by Mann–Whitney non-parametric test (*p < 0.05; **p < 0.01; ***p < 0.001). p and r values for associations were determined by Spearman's correlation test, with linear regression shown as a line. Significant (p < 0.05) values are in bold.