Table 1.
Baseline characteristics
| Characteristic | Vertigo (−), n = 27 | Vertigo (+), n = 32 | p‐value |
|---|---|---|---|
| Age in years, median (IQR) | 66 (55–77) | 70 (54–79) | .88 |
| Women, n (%) | 6 (22.2) | 15 (46.9) | .049* |
| Active smoking, n (%) | 6 (22.2) | 6 (18.8) | .74 |
| Hypertension, n (%) | 22 (81.5) | 26 (81.3) | .98 |
| Diabetes, n (%) | 2 (7.4) | 5 (15.6) | .44 |
| Atrial fibrillation, n (%) | 6 (22.2) | 9 (28.1) | .6 |
| History of previous stroke, n (%) | 7 (25.9) | 4 (12.5) | .32 |
| HbA1c%, median (IQR) | 5.6 (5.3–6.2) | 5.6 (5.3–5.8) | .82 |
| LDL‐Cholesterol (mg/dl), median (IQR) | 108 (83–121) | 113.5 (84.8–147) | .36 |
| Headache, n (%) | 6 (24) | 14 (45.2) | .1 |
| Absence of focal neurological deficits, n (%) | 1 (3.7)c | 11 (34.4) | .004* |
| NIHSS on admission, median (IQR) | 2 (1–5) | 2 (0–4) | .16 |
| Good outcome on discharge, n (%)a | 22 (81.5) | 25 (78.1) | .75 |
| Onset of symptoms till presentation in hours, median (IQR)b | 4 (2–12) | 7.5 (4–46) | .052 |
| Bilateral infarction, n (%) | 5 (18.5) | 7 (21.9) | .75 |
| Infarction location, n (%) | |||
| Cerebellum or brainstem | 14 (51.9) | 30 (93.8) | <.001* |
| Cerebellum or dorsal brainstem | 11 (40.7) | 29 (90.6) | <.001* |
| Cerebellum | 9 (33.3) | 26 (81.3) | <.001* |
| Cerebellar tonsil | 2 (7.4) | 15 (46.9) | .001* |
| Cerebellar nodulus | 1 (3.7) | 7 (21.9) | .06 |
| Dorsal brainstem | 3 (11.1) | 7 (21.9) | .32 |
| Total infarction volume in cm3, median (IQR) | 0.42 (0.14–8.4) | 5.6 (0.98–25.5) | .008* |
| Total infarction volume of >0.48 cm3, n (%) | 12 (44.4) | 27 (84.4) | .002* |
| Volume of infarctions located in the cerebellum >0.36 cm3, n/N (%) | 2/9 (22.2) | 25/26 (96.2) | <.001* |
| Volume of infarction located in the cerebellum and/or brainstem, median (IQR) |
0.24 (0.11–0.38) (n = 14) |
5.6 (0.77–24.01) (n = 30) |
<.001* |
| Volume of infarction located in the cerebellum, median (IQR) |
0.26 (0.12–4.92) (n = 9) |
9.09 (2.4–25.26) (n = 26) |
.001* |
| Volume of infarction located in the brainstem, median (IQR) |
0.11 (0.05–0.27) (n = 7) |
0.10 (0.05–0.5) (n = 9) |
.92 |
| Intravenous thrombolysis, n (%) | 10 (37) | 5 (15.6) | .06 |
Abbreviations: HbA1c, hemoglobin A1c; IQR, interquartile range; LDL‐cholesterol, low‐density lipoprotein cholesterol; NIHSS, National Institute of Health Stroke Scale.
Good outcome on discharge was defined as modified Rankin Scale ≤ 2 on discharge.
In patients with wake‐up stroke or those found with stroke, the time, when the patient was found with stroke, was used to denote the time of symptom onset.
The patient presented with transient episodes of blurring vision in both eyes. In addition, the patient had nausea and vomiting without vertigo. MRI brain showed a small right cerebellar infarction.
Statistically significant results.