. 2020 Feb 4;200(1):12–21. doi: 10.1111/cei.13413

Table 1.

Phenotypical characteristics of different immune cells expressing CD28H

Immune cells	Naive T cells		Effector memory T cell		Central memory T cell	NK cell
CH28H expression	CD28H⁺ a	CD28H⁻ b	CD28H⁺	CD28H⁻	CD28H⁺	CD28H⁺
CD45RA	Mostc ^,2	Littlec ^,2	Mediumc ^,2		Medium²
CA45RO		Most²		Most²
CCR7	Most²		Medium²		Medium²
CD31	Highd ^,3	Lowd ^,3
T‐bet	Low³	High³
IFN‐γ	Low³	High³	Low⁷	Low⁷	Low³
TNF‐α	Low³	High³
CD28	High³	Low³
IL‐2	Similard ^,3	Similar³
CXCL8	Similar³	Similar³
CD7		Low^2,3,32–35		Low^2,3,32–35
CD27		Little^2,3,32–35		Little^{2 3,32–35}
CD28		Little^{2,3 32–35}		Little^2,3,32–35
CD57	Low³	Most^2,3,32–35	Low³	Most^{2,3 32–35}	Low³
KIR						Little⁴
NKG2A						Most⁴
CD56						Little⁴

CD28H⁺: immune cells express CD28H‐positive.

CD28H⁻: immune cells express CD28H‐negative.

Most, medium and little: percentage of CD28H⁺ or CD28H⁻ immune cells expressing different cell surface molecules.

High, similar and low: comparison of expression levels of different cell surface molecules in CD28H⁺ and CD28H⁻ T cells.

IFN = interferon; TNF = tumor necrosis factor; IL = interleukin; CXCL8 = C‐X‐C motif chemokine ligand 8; KIR = killer immunoglobulin‐like receptors.