Figure 3.

At-EE decreased ovarian cancer-mediated angiogenesis. (a–d) HUVEC cells were treated by condition media from ovarian cancer cells treated by At-EE or DMSO. (a) Representative diagram of the coculture assay. (b) Wound healing assays were done for the mobility of HUVEC cells. (c) Cell invasion assays were done for metastasis of HUVEC cells. (d) In vitro angiogenesis evaluation was done for HUVEC cells. The results were similar in at least three independent experiments. ^∗p < 0.05. ^∗∗p < 0.01.