Table 3.

Adjusted OS by diagnosis: DCIS (N = 158,241), invasive non-metastatic (N = 915,994), and invasive metastatic (N = 38,813)

	Hazard ratio (95% CI)	p value	Overall p value
DCIS
Age group (years)			< 0.001
≤ 45	Ref
46–74	2.187 (1.928–2.48)	< 0.001
≥ 75	7.191 (6.28–8.235)	< 0.001
Invasive, non-metastatic
Age group (years)			< 0.001
≤ 45	Ref
46–74	1.207 (1.179–1.237)	< 0.001
≥ 75	3.057 (2.965–3.151)	< 0.001
Invasive, metastatic
Age group (years)			< 0.001
≤ 45	Ref
46–74	1.166 (1.117–1.218)	< 0.001
≥ 75	1.566 (1.479–1.659)	< 0.001

All models adjusted for year of diagnosis, gender, race/ethnicity, insurance status, income level, education level, facility type, facility location, distance traveled, Charlson/Deyo Comorbidity Score, histology, tumor grade, clinical T stage, clinical N stage, estrogen receptor status, progesterone receptor status, surgery type, radiation therapy, chemotherapy, and endocrine therapy

DCIS ductal carcinoma in situ