Table 1:

Study characteristics of therapeutic hypothermia trials.

	Included patient demographics	Patients enrolled	Mortality	Good neurologic outcome	Limitations
HACA	VT/VF survivors, TH induced <60 minutes, 24 hours of TH	TH-138	TH-41%	TH-55%	Pyrexia in control subjects, select study population.
		Control-137	Control-55%	Control-39%
Bernard	VF survivors, TH induced < 2 hours, 12 hours of TH	TH-43	TH-51%	TH-49%	Small study population, 8% of assessed patients were included in study
		Control-34	Control-68%	Control-26%
De-Sa	VT/VF survivors, TH induced < 60 minutes, 24 hours of TH	32°C– 18	32°C– 56%	32°C– 69%	Small study population.
		34°C– 18	34°C– 89%	34°C– 23%
TTM	Cardiac etiology of arrest, TH induced < 4 hours, 28 hours of temperature management	33°C– 476	33°C– 50%	33°C– 54%	Conducted in European and Australian centers, may not reflect other countries outcomes.
		36°C– 474	36°C– 48%	36°C– 52%