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. 2020 Mar 11;10(1):2045894018807205?. doi: 10.1177/2045894018807205

Fig. 4.

Fig. 4.

Gremlin 1 attenuates VEGFA induced increases in human lung microvascular endothelial cell number. (a) Numbers of human microvascular endothelial cells from the lung (HMVEC-L) after exposure for 24 h to vehicle alone, vehicle and gremlin 1 (2 µg/mL), VEGFA (1 ng/mL) alone, VEGFA (1 ng/mL) together with gremlin 1 (2 µg/mL), VEGFA (8 ng/mL) alone, or VEGFA (8 ng/mL) together with gremlin 1 (2 µg/mL). Cell counts are expressed relative to control number (vehicle) in each experiment. (b) Numbers of HMVEC-L after exposure to vehicle alone, vehicle and gremlin 1 (2 µg/mL), BMP2 (50 ng/mL) alone, BMP2 (50 ng/mL) together with gremlin 1 (2 µg/mL), BMP2 (100 ng/mL) alone, or BMP2 (100 ng/mL) together with gremlin 1 (2 µg/mL) for 24 h. Cell counts are expressed relative to control number (vehicle) in each experiment. Bars represent mean ± SD.