Table 2.
Group comparison of diffusion coefficients in major white matter tracts
| Major tract | OSA mMean FA (SD) | Control mean FA (SD) | Tract-wise corrected P* | OSA mean MD (×10−3 mm2/s) | Control mean MD (×10−3 mm2/s) | Tract-wise corrected P* |
|---|---|---|---|---|---|---|
| LH ATR | 0.248 (0.1506) | 0.271 (0.1476) | 0.0096 | 0.812 | 0.807 | 0.5197 |
| LH CST | 0.4478 (0.1567) | 0.423 (0.1478) | 0.5190 | 0.629 | 0.594 | – |
| LH CG | 0.2788 (0.1722) | 0.271 (0.1624) | 0.0859 | 0.658 | 0.631 | 0.6016 |
| LH IFO | 0.2420 (0.1159) | 0.251 (0.1220) | 0.4252 | 0.6510 | 0.621 | 0.4051 |
| LH ILF | 0.2392 (0.1027) | 0.246 (0.1022) | 0.1136 | 0.574 | 0.583 | 0.3701 |
| LH SLF | 0.3326 (0.1582) | 0.354 (0.1469) | 0.2698 | 0.606 | 0.568 | 0.2522 |
| LH UNC | 0.2098 (0.1120) | 0.2083 (0.1014) | 0.6680 | 0.750 | 0.710 | 0.0085 |
| RH ATR | 0.3133 (0.1768) | 0.3195 (0.1411) | 0.0047 | 0.579 | 0.553 | 0.0924 |
| RH CST | 0.3739 (0.1872) | 0.3772 (0.1818) | 0.0837 | 0.684 | 0.667 | 0.4474 |
| RH CG | 0.2506 (0.1228) | 0.2468 (0.1220) | 0.4067 | 0.554 | 0.536 | 0.1514 |
| RH IFO | 0.2455 (0.1514) | 0.2590 (0.1552) | 0.1042 | 0.656 | 0.626 | 0.6467 |
| RH ILF | 0.3012 (0.1379) | 0.3099 (0.1559) | 0.1940 | 0.594 | 0.560 | 0.2790 |
| RH SLF | 0.2917 (0.1526) | 0.2916 (0.1527) | 0.3353 | 0.570 | 0.539 | 0.5092 |
| RH UNC | 0.1813 (0.1052) | 0.1897 (0.1149) | 0.0083 | 0.758 | 0.719 | 0.6300 |
OSA, obstructive sleep apnea; FA, fractional anisotropy; SD, standard deviation; MD, mean diffusivity; LH, left hemisphere; RH, right hemisphere; ATR, anterior thalamic radiation; CST, corticospinal tract; CG, cingulum; IFO, inferior fronto-occipital fasciculus; ILF, inferior-longitudinal fasciculus; SLF, superior-longitudinal fasciculus; UNC, uncinate fasciculus. Bold values denote statistical significance at the p < 0.05 level.
*The lowest p-value from the cluster-based statistics for each fiber tract.