. 2020 Mar 11;5(5):1–10. doi: 10.1001/jamacardio.2020.0140

Table 3. Association Between Carotid Intima-Media Thickness and Clinical CVH Score Trajectory Group.

Clinical CVH score trajectory group^a	Carotid intima-media thickness, mm
	Adjusted^b		Adjusted and baseline score^c		Adjusted and proximal score^d
	Point estimate, mean (95% CI)	P Value	Point estimate, mean (95% CI)	P Value	Point estimate, mean (95% CI)	P Value
High-late decline	0.64 (0.63-0.65)	NA	0.72 (0.69-0.75)	NA	0.71 (0.68-0.74)	NA
High-moderate decline	0.67 (0.64-0.69)	<.001	0.75 (0.71-0.79)	<.001	0.72 (0.68-0.77)	.04
High-early decline	0.69 (0.67-0.71)	<.001	0.76 (0.72-0.80)	<.001	0.73 (0.69-0.78)	.003
Intermediate-late decline	0.67 (0.64-0.69)	<.001	0.74 (0.69-0.78)	.02	0.73 (0.68-0.77)	.02
Intermediate-early decline	0.72 (0.69-0.75)	<.001	0.78 (0.73-0.83)	<.001	0.75 (0.70-0.80)	<.001

Abbreviations: cIMT, carotid intima-media thickness; CVH, cardiovascular health; NA, not applicable.

^{^a}

Calculation of the CVH score is detailed in the CVH Scores subsection of the Methods section.

^{^b}

Adjusted for age, sex, race, cohort, maternal and paternal educational level, baseline smoking, physical activity, and diet scores.

^{^c}

Adjusted for age, sex, race, cohort, maternal and paternal educational level, baseline smoking, physical activity, diet scores, and baseline CVH score. Baseline CVH score was the earliest recorded CVH score per participant.

^{^d}

Adjusted for age, sex, race, cohort, maternal and paternal educational level, baseline smoking, physical activity, diet scores, and proximal CVH score. Proximal CVH score was the clinical CVH score from the examination at or before the cIMT measurement.