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. 2020 Mar 10;5(1):e000304. doi: 10.1136/bmjophth-2019-000304

Table 3.

Risk factors associated with the prevalence of diabetic retinopathy in subjects with recently diagnosed type 2 diabetes stratified by diabetes duration

Whole sample Stratified by duration of diabetes
<1–2 years 3–5 years
Unadjusted
OR (95% CI)
Adjusted
OR (95% CI)
Adjusted
OR (95% CI)
Adjusted
OR (95% CI)
Age at diabetes diagnosis (per 5 years) 0.93 (0.88 to 0.99) * 0.93 (0.85 to 1.00) 0.89 (0.82 to 0.98) * 1.00 (0.86 to 1.16)
Sex (men) 1.81 (1.34 to 2.44) *** 1.81 (1.33 to 2.46) *** 1.80 (1.18 to 2.73) ** 1.83 (1.14 to 2.95) *
Duration of diabetes (per year) 1.27 (1.16 to 1.40) *** 1.20 (1.10 to 1.32) ***
Duration of diabetes (years)
 <1 Reference
 1–2 1.01 (0.67 to 1.52)
 3–5 2.24 (1.58 to 3.18) ***
HbA1c (mmol/mol) 1.15 (1.09 to 1.21) ***
HbA1c (%)
 <7 Reference Reference Reference Reference
 7.0–8.9 2.17 (1.33 to 3.53)** 2.19 (1.43 to 3.35)*** 1.86 (1.11 to 3.12)* 3.37 (1.52 to 7.50)**
 ≥9 3.07 (2.13 to 4.42)*** 2.98 (2.01 to 4.42)*** 1.94 (1.18 to 3.19)** 6.22 (2.96 to 13.09)***
Hypertension 1.59 (1.18 to 2.14)**
SBP (per 5 mm Hg) 1.14 (1.09 to 1.19) *** 1.16 (1.10 to 1.22) *** 1.13 (1.06 to 1.21) *** 1.21 (1.11 to 1.32) ***
DPB (per 5 mm Hg) 1.28 (1.16 to 1.40) ***
Triglycerides≥1.68 mmol/L 1.25 (0.91 to 1.71)
Albuminuria 2.11 (1.47 to 3.02) ***
Antihypertensive drugs 1.08 (0.77 to 1.52) 0.95 (0.64 to 1.41) 1.03 (0.60 to 1.77) 0.85 (0.47 to 1.55)
Statin use 1.21 (0.70 to 2.11)

Simple and multiple robust logistic regression analysis was used to estimate ORs and their 95% CIs.

Whole sample, n=1232; subsample with diabetes duration of <1–2 years, n=823; and subsample with a diabetes duration from 3 to 5 years, n=409. Missing values: albuminuria, 29.

*P<0.05, **P<0.01, ***P<0.001.

DBP, diastolic blood pressure; HbA1c, haemoglobin A1c; SBP, systolic blood pressure.