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| Methods | RCT Concealment of allocation unclear Blindness double Duration 28 days | |
| Participants | Diagnosis Unipolar Depression RDC HAMD >18 Outpatients (Psych) N=60 Sex 23M, 37F Mean age = 68.4 | |
| Interventions | 1. Placebo N=20 2. Trazodone N=19 100 ‐ 400mg/d 3. Imipramine N=21 50 ‐ 200mg/d | |
| Outcomes | HAM‐D HAMA BDI TESS Effects on cognition ECG | |
| Notes | ||
| Risk of bias | ||
| Bias | Authors' judgement | Support for judgement |
| Allocation concealment? | Unclear risk | B ‐ Unclear |
