Kane 1983.
Methods | RCT Concealment of allocation unclear Blindness double Duration 28 days | |
Participants | Diagnosis depressed mood and 4 associated symptoms HAM‐D >18 Outpatients (Psych) N=44 Sex 13M, 31F Mean age = 63.9+6.98 | |
Interventions | 1. Placebo N=7 2. Bupropion (LD)N =11 150mg/d 3. Bupropion (HD)N=13 300mg/d 4. Imipramine N=13 75‐200mg/d | |
Outcomes | HAM‐D HAMA CGI Zung SDS Zung SAS | |
Notes | ||
Risk of bias | ||
Bias | Authors' judgement | Support for judgement |
Allocation concealment? | Unclear risk | B ‐ Unclear |