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. 2001 Jan 22;2001(1):CD000561. doi: 10.1002/14651858.CD000561

Merideth 1984.

Methods RCT 
 Concealment of allocation unclear 
 Blindness double 
 Duration 35 days
Participants Diagnosis Primary Depressive Disorder Feighner Criteria 
 HAM‐D >18 
 Inpatients 
 N=61 
 Sex 16M, 45F 
 Mean age = ˜68
Interventions 1. Placebo N=19 
 2. Nomifensine N=22 
 50 ‐ 200mg/d 
 3. Imipramine N=20 
 50 ‐ 200mg/d
Outcomes HAM‐D 
 CGI
Notes  
Risk of bias
Bias Authors' judgement Support for judgement
Allocation concealment? Unclear risk B ‐ Unclear