Nair 1995.
Methods | RCT Concealment of allocation unclear Blindness double Duration 49 days | |
Participants | Diagnosis Major Depressive Disorder DSMIIIR HAM‐D >18 CGI >Moderate Unknown recruitment N=109 Sex 32M, 77F Mean age = ˜69 | |
Interventions | 1. Placebo N=35 2. Moclobemide N=36 100 ‐400mg/d 3. Nortriptyline N=38 25 ‐75mg/d to serum levels 50‐170ng/ml | |
Outcomes | GDS HAM‐D CGIS MMSE CGIE CGIT | |
Notes | ||
Risk of bias | ||
Bias | Authors' judgement | Support for judgement |
Allocation concealment? | Unclear risk | B ‐ Unclear |