Skip to main content
. 2020 Feb 21;5(9):4682–4688. doi: 10.1021/acsomega.0c00123

Table 3. Stability of Selegiline in Rat Plasmae.

nominal concentration (ng/mL) autosamplera stability (%) short-termb stability (%) long-termc stability (%) freeze–thawd stability (%)
5 89.83 ± 3.86 90.43 ± 2.57 88.63 ± 2.32 66.36 ± 1.79
50 100.1 ± 6.97 91.19 ± 7.33 87.75 ± 1.44 59.40 ± 0.68
500 96.43 ± 8.44 83.43 ± 8.81 88.69 ± 3.41 67.27 ± 1.42
a

Autosampler stability: the sample was placed in an autosampler at 10 °C for 6 h.

b

Short-term stability: the sample was placed in plasma at 4 °C for 6 h.

c

Long-term stability: the sample was placed in plasma at −20 °C for 2 weeks.

d

Freeze–thaw stability: the sample was placed in plasma at −20 °C for 12 h and then at room temperature for 12 h, and this cycle was repeated three times.

e

Formulation = (peak area of processed sample/peak area of freshly prepared sample) × 100.