Kaplan‐Meier curves in patients stratified according to treatment arm, for DFS and OS, respectively, in MSI‐high versus MSS patients’ subgroups (A, B), high versus low inflammatory reaction (C, D), tumor PD‐L1 expression ≥1% versus <1% (E, F).Abbreviations: 5‐FU/LV, 5‐fluorouracil plus leucovorin; DFS, disease‐free survival; MSI, microsatellite instability; MSS, microsatellite stable; OS, overall survival; tPD‐L1, percentage of stained tumor.