Table 2.
Biochemical parameters of normotensive subjects and controlled hypertensive patients and those in hypertensive crisis (divided in hypertensive urgency and emergency)
| Variable | NT (n = 40)a |
CHyp (n = 58)b |
HypUrg (n = 43)c |
HypEmerg (n = 57)d |
p value (axbxcxd) |
a x b | a x c | a x d | b x c | b x d | c x d |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Biochemical parameters | |||||||||||
| Glycemia (mg/dL) | 86.6 ± 16.7 | 104.8 ± 42.6 | 121.5 ± 45.5 | 149.7 ± 96.3 | <0.0001 | 0.007 | 0.002 | 0.003 | 0.04 | 0.04 | 0.66 |
| HDL-c (mg/dL) | 61.2 ± 12.2 | 53 ± 13.2 | 52.6 ± 19.8 | 48.1 ± 16.4 | 0.008 | 0.02 | 0.004 | 0.006 | 0.001 | 0.002 | 0.004 |
| LDL-c (mg/dL) | 115.2 ± 23.3 | 123.6 ± 31.8 | 127.1 ± 38.5 | 109.3 ± 44.8 | 0.03 | 0.09 | 0.18 | 0.08 | 0.84 | 0.70 | 0.01 |
| Cholesterol (mg/dL) | 198.6 ± 22.1 | 204.3 ± 37.4 | 210.7 ± 49 | 184.6 ± 52.4 | 0.009 | 0.47 | 0.37 | 0.61 | 0.43 | 0.11 | 0.06 |
| TG (mg/dL) | 110.4 ± 48.1 | 137.2 ± 59.1 | 142.7 ± 69.3 | 130.1 ± 77.7 | 0.87 | – | – | – | – | – | – |
| Creatinine (mg/dL) | 0.85 ± 0.21 | 0.86 ± 0.18 | 1.55 ± 1.65 | 1.83 ± 1.65 | 0.001 | 0.26 | 0.03 | 0.008 | 0.03 | 0.009 | 0.38 |
| GFR (mL/min/1.73m2) | 94.4 ± 17.7 | 87.7 ± 16.5 | 70.8 ± 36.1 | 59.9 ± 34.5 | <0.0001 | 0.31 | 0.002 | 0.0002 | 0.01 | 0.0007 | 0.12 |
| Uric acid (mg/dl) | 3.8 ± 1.01 | 5.7 ± 1.43 | 6.5 ± 2.17 | 6.2 ± 2.15 | <0.0001 | 0.007 | 0.001 | 0.002 | 0.68 | 0.17 | 0.54 |
| Potassium (mEq/L) | 4.25 ± 0.37 | 4.34 ± 0.57 | 4.55 ± 0.87 | 4.47 ± 0.83 | 0.16 | – | – | – | – | – | – |
| LogMMP-9 | 1.94 ± 0.3 | 1.92 ± 0.2 | 2.17 ± 0.3 | 2.31 ± 0.2 | < 0.0001 | 0.60 | 0.05 | 0.0003 | 0.001 | 0.0006 | 0.94 |
Values are means ± standard deviation
NT normotensive group, CHyp controlled hypertensive group, HypUrg hypertensive urgency, HypEmerg hypertensive emergency, HDL-c high-density lipoprotein cholesterol, LDL-c low-density lipoprotein, TG Triglycerides, GFR glomerular filtration rate