Table 1.
Baseline characteristics of patients for validation
| Characteristics | HSPN (n = 30) | Normal (n = 29) | HSP (n = 10) |
|---|---|---|---|
| Onset age (years) | 9.4 ± 2.4 | 8.8 ± 2.9 | 9.3 ± 2.5 |
| Male gender n (%) | 20(66.7%) | 12(41.4%) | 6(60%) |
| Presenting symptoms n (%) | |||
| Macro or microscopic hematuria | 30(100%) | – | – |
| Proteinuria | 27(90%) | – | – |
| Purpuric rash | 30(100%) | – | 10 (100%) |
| Colicky pain | 13(43.3%) | – | 6(60%) |
| Arthralgia | 11(36.7%) | – | 5(50%) |
| Edema | – | – | – |
| Bloody stools | – | – | – |
| Renal pathology n (%) | |||
| IgA mesangial deposition | 30(100%) | – | – |
| Mesangial proliferation | 30(100%) | – | – |
| Crescents | 15(50%) | – | – |
| Segmental glomerulosclerosis | 13(43.3%) | – | – |
| Laboratory measurements | |||
| Serum IgA levels (g/l) | 1.8 ± 0.5 | – | 1.9 ± 0.3 |
| Serum IgE levels (IU/ml) | 193.3 ± 182.9 | – | 285.3 ± 106.7 |
| Serum creatinine (μmol/l) | 36.0 ± 8.5 | – | 34.0 ± 5.4 |
| eGFR (ml/min/1.73 m2) | 200.7 ± 31.3 | – | 203.8 ± 15.3 |
eGFR is estimated by the Schwartz formula [K* height (cm)/serum creatinine (μmol/L)]
HSPN Henoch-Schönlein purpura nephritis, Normal healthy controls, HSP Henoch-Schönlein purpura, eGFR estimated glomerular filtration rate