. 2020 Mar 12;20:208. doi: 10.1186/s12885-020-6698-6

Table 1.

Correlation between inflammatory parameters and clinicopathological characteristics

Parameters	NO. (154)	NLR	P value	PLR	P value	LMR	P value	PNI	P value
Parameters	NO. (154)	Low (124) /High (30)	P value	Low (84) / High (70)	P value	Low (59) /High (95)	P value	Low (32) /High (122)	P value
Age			0.054		0.622		0.558		0.441
≤ 60 years	54	48/6		28/26		19/35		8/46
> 60 years	100	76/24		56/44		40/60		24/98
Gender			0.308		0.720		0.063		0.184
Male	90	70/20		48/42		40/50		22/68
Female	64	54/10		36/28		19/45		10/54
Smoking			0.650		0.183		0.628		0.815
Yes	41	34/7		26/15		17/24		8/33
No	113	90/23		58/55		42/71		24/89
Alcoholism			0.780		0.079		0.720		0.962
Yes	39	32/7		26/13		14/25		8/31
No	115	92/23		58/57		45/70		24/91
Hypertension			0.917		0.382		0.373		0.555
Yes	45	36/9		27/18		16/29		8/37
No	109	88/21		57/52		43/56		24/85
Diabetes Mellitus			1.000		0.165		0.839		0.240
Yes	22	18/4		15/7		8/14		2/20
No	132	106/26		69/63		51/81		30/102
Coronary Artery Disease			0.153		0.247		0.056		0.216
Yes	21	14/7		9/12		12/9		7/14
No	133	110/23		75/58		47/86		25/108
CEA			0.415		0.593		0.023		0.261
< 5 μg/ml	126	103/23		70/56		43/83		24/102
≥ 5 μg/ml	28	21/7		14/14		16/12		8/20
CA19–9			1.000		0.127		0.515		1.000
< 37 U/ml	147	118/29		78/69		55/92		31/116
≥ 37 U/ml	7	6/1		6/1		4/3		1/6
HGB			0.063		0.012		0.854		0.013
≥ 110 g/L	143	118/25		82/61		54/89		26/117
< 110 g/L	11	6/5		2/9		5/6		6/5
Occult blood			0.967		0.169		0.190		0.831
Yes	128	103/25		73/55		52/76		27/101
No	26	21/5		11/15		7/19		5/21
Distance from anal verge			0.838		0.877		0.103		0.355
≤ 50 mm	54	43/11		29/25		16/38		9/45
> 50 mm	100	81/19		55/45		43/57		23/77
Operation procedure			0.945		0.010		0.149		0.446
TEM	47	38/9		33/14		14/33		8/39
Radical resection	107	86/21		51/56		45/62		24/83
Time of operation			0.645		0.067		0.125		0.165
< 3 h	56	44/12		36/20		17/39		15/41
≥ 3 h	98	80/18		48/50		42/56		17/81
Blood transfusion perioperation			0.024		0.626		0.973		0.191
Yes	4	1/3		3/1		1/3		2/2
No	150	123/27		81/69		58/92		30/120
Differentiation grade			0.195		0.118		0.458		0.349
Well+Moderate	126	99/27		65/61		50/76		28/98
Poor+Undifferentiate	28	25/3		19/9		9/19		4/24
Tumor size			0.003		0.575		0.111		0.764
< 3 cm	83	66/17		47/36		27/56		18/65
≥ 3 cm	71	68/3		37/34		32/39		14/57
T stage			0.389		0.952		0.052		0.255
T1	62	52/10		34/28		18/44		14/48
T2	92	72/20		50/42		41/51		18/74
N stage			0.901		0.064		< 0.001		0.096
N0	132	107/25		76/56		42/90		24/108
N1/2	22	17/5		8/14		17/5		8/14
TNM stage			0.901		0.064		< 0.001		0.096
I	132	107/25		76/56		42/90		24/108
III	22	17/5		8/14		17/5		8/14

NLR neutrophil-to-lymphocyte ratio; PLR platelet-to-lymphocyte ratio; LMR lymphocyte-to-monocyte ratio; PNI prognostic nutritional index; CEA carcinoembryonic antigen; CA19–9 carbohydrate antigen 19–9; HGB hemoglobin; TEM transanal endoscopic microsurgery; TNM tumor-lymph node-metastasis