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. 2020 Mar 12;20:207. doi: 10.1186/s12885-020-6704-z

Table 1.

Patient characteristics

All (n = 62) DR (n = 11) True PD (n = 51) P
n n % n %
Age median 65, range 27–82
≥75 11 2 18 9 18 1.000
< 75 51
Gender Male 40 7 64 33 65 1.000
Female 22
Performance status 0,1 46 8 73 38 75 1.000
2–4 16
Smoking status Current/former 45 6 55 39 76 0.155
Never 17
Histology Squamous cell carcinoma 12 2 18 10 20 1.000
Non-squamous cell carcinoma 50
Adenocarcinoma (n = 46), Others (n = 4)
Driver mutation Positive 15 3 27 12 24 0.696
EGFR L858R/19del (n = 12), ALK (n = 3)
Negative 47
Line of treatment 2nd line 32 7 64 25 49 0.511
3rd line or beyond 30
PD-L1 status <  1 8 0 0 8 16
1 ≤ 28 7 64 21 41
Unknown 26 4 40 22 43
Treatment Nivolumab 45 9 20 36 80
Pembrolizumab 7 2 29 5 71
Atezolizumab 10 0 0 10 100

Abbreviations: DR dissociated responses, PD-L1 programmed cell death-ligand 1, True PD true progressive disease