Table 3.

Univariate and multivariate analyses used for differentiating significant predictors to distinguish AFP-NHCC from healthy controls

Variables	Univariate analysis			Multivariate analysis
	OR	95% CI	P-value	OR	95% CI	p-value
Gender	0.588	0.312–1.106	0.099
Age(y)	1.013	0.992–1.035	0.232
TBIL	1.086	1.039–1.134	< 0.001	1.110	0.985–1.250	0.086
AST	1.232	1.175–1.293	< 0.001	1.079	0.969–1.200	0.166
ALT	1.133	1.101–1.167	< 0.001	1.081	1.011–1.157	0.023
ALP	1.023	1.013–1.033	< 0.001	0.997	0.970–1.024	0.806
FPR	2.082	1.783–2.430	< 0.001	2.320	1.824–2.949	< 0.001
GPR	1.748 × 108	2.003 × 106–1.525 × 1010	< 0.001	8.260 × 106	5.031 × 103–1.356 × 1010	< 0.001

TBIL total bilirubin, ALT alanine aminotransferase, AST aspartate amino transferase, ALP alkaline phosphatase, FPR fibrinogen to pre-albumin ratio, GPR gamma-glutamyl transpeptidase to platelet ratio, CI confidence interval, OR odd ratio, AFP-NHCC alpha-fetoprotein-negative hepatocellular carcinoma