Table 2.
The prevalence and frequency of ophthalmic disorders in the systemic lupus erythematosus cohort and comparison cohort (N = 5731)
| Variable | N (%) | P | |||
|---|---|---|---|---|---|
| systemic lupus erythematosus cohort 521 (9.1) | comparison cohort 5210 (90.9) | ||||
| Ophthalmologist visits | |||||
| Prevalence (%) | 355 | (68.1) | 3151 | (60.5) | 0.001 |
| Number of visits, median (IQR) (/10 years) | 5.51 | (0–21.28) | 1.71 | (0–7.02) | < 0.001 |
| Number of visits, mean (SD) (/10 years) | 21.15 | (42.22) | 7.98 | (18.50) | |
| Chronic conjunctivitis (excluding chronic allergic conjunctivitis) | |||||
| Prevalence (%) | 258 | (50.5) | 1568 | (30.1) | < 0.001 |
| Number of visits, median (IQR) (/10 years) | 0 | (0–3.58) | 0 | (0–1.07) | < 0.001 |
| Number of visits, mean (SD) (/10 years) | 3.81 | (8.01) | 1.94 | (7.30) | |
| Dry eye syndrome | |||||
| Prevalence (%) | 144 | (27.6) | 365 | (7.0) | < 0.001 |
| Number of visits, median (IQR) (/10 years) | 0 | (0–0.98) | 0 | (0–0) | < 0.001 |
| Number of visits, mean (SD) (/10 years) | 2.97 | (9.65) | 0.46 | (3.71) | |
| Acute and chronic allergic conjunctivitis | |||||
| Prevalence (%) | 108 | (20.7) | 681 | (13.1) | < 0.001 |
| Number of visits, median (IQR) (/10 years) | 0 | (0–0) | 0 | (0–0) | < 0.001 |
| Number of visits, mean (SD) (/10 years) | 0.95 | (3.70) | 0.51 | (3.26) | |
| Keratitis (excluding dry eye syndrome) | |||||
| Prevalence (%) | 90 | (17.3) | 437 | (8.4) | < 0.001 |
| Number of visits, median (IQR) (/10 years) | 0 | (0–0) | 0 | (0–0) | < 0.001 |
| Number of visits, mean (SD) (/10 years) | 1.03 | (4.50) | 0.28 | (1.76) | |
| Refractive disorders | |||||
| Prevalence (%) | 90 | (17.3) | 315 | (6.0) | < 0.001 |
| Number of visits, median (IQR) (/10 years) | 0 | (0–0) | 0 | (0–0) | < 0.001 |
| Number of visits, mean (SD) (/10 years) | 0.75 | (3.28) | 0.18 | (1.20) | |
| Acute conjunctivitis (excluding acute allergic conjunctivitis) | |||||
| Prevalence (%) | 88 | (16.9) | 545 | (10.5) | < 0.001 |
| Number of visits, median (IQR) (/10 years) | 0 | (0–0) | 0 | (0–0) | < 0.001 |
| Number of visits, mean (SD) (/10 years) | 0.52 | (1.80) | 0.28 | (1.97) | |
| Cataracts | |||||
| Prevalence (%) | 85 | (16.3) | 431 | (8.3) | < 0.001 |
| Number of visits, median (IQR) (/10 years) | 0 | (0–0) | 0 | (0–0) | < 0.001 |
| Number of visits, mean (SD) (/10 years) | 1.97 | (7.05) | 0.84 | (4.98) | |
| Hordeolum | |||||
| Prevalence (%) | 73 | (14.0) | 637 | (12.2) | 0.238 |
| Number of visits, median (IQR) (/10 years) | 0 | (0–0) | 0 | (0–0) | 0.224 |
| Number of visits, mean (SD) (/10 years) | 0.40 | (1.49) | 0.31 | (1.19) | |
| Retina disorder | |||||
| Prevalence (%) | 44 | (8.4) | 202 | (3.9) | < 0.001 |
| Number of visits, median (IQR) (/10 years) | 0 | (0–0) | 0 | (0–0) | < 0.001 |
| Number of visits, mean (SD) (/10 years) | 0.87 | (6.32) | 0.31 | (2.96) | |
| Glaucoma | |||||
| Prevalence (%) | 20 | (3.8) | 133 | (2.6) | 0.083 |
| Number of visits, median (IQR) (/10 years) | 0 | (0–0) | 0 | (0–0) | 0.085 |
| Number of visits, mean (SD) (/10 years) | 0.52 | (4.29) | 0.61 | (6.71) | |
| Primary open-angle glaucoma | |||||
| Prevalence (%) | 2 | (0.4) | 27 | (0.5) | 0.680 |
| Number of visits, median (IQR) (/10 years) | 0 | (0–0) | 0 | (0–0) | |
| Number of visits, mean (SD) (/10 years) | 0.07 | (1.44) | 0.13 | (2.42) | 0.680 |
P values were obtained by Chi-square test for comparison of prevalence and Mann-Whitney U-test for comparison of medians of number of visits
IQR Interquartile range, SD Standard deviation