Table 3.
The incidence rate and incidence risk ratio of dry eye syndrome in the systemic lupus erythematosus cohort and comparison cohort (N = 5393)
| Disorder (ICD-9-CM) | SLE cohort (n = 450) | comparison cohort (n = 4943) | IRR (95% CI) | Adjusted IRRa (95% CI) | |||||
|---|---|---|---|---|---|---|---|---|---|
| No. of patient | Person-years | IR | No. of patient | Person-years | IR | P | P | ||
| Dry eye syndrome (375.15, 710.2, 370.33) | Overall | 107 | 2577 | 41.52 | 298 | 32,189 | 9.26 | 4.48 (3.60–5.59) < 0.001 | 4.45 (3.54–5.58) < 0.001 |
| Sex | |||||||||
| male | 9 | 259 | 34.75 | 29 | 3472 | 8.35 | 4.16 (1.97–8.78) < 0.001 | 4.46 (2.08–9.58) < 0.001 | |
| female | 98 | 2318 | 42.28 | 269 | 28,717 | 9.37 | 4.51 (3.58–5.69) < 0.001 | 4.45 (3.50–5.65) < 0.001 | |
| Age group (years) | |||||||||
| 20–39 | 50 | 1564 | 31.97 | 126 | 18,357 | 6.86 | 4.66 (3.37–6.46) < 0.001 | 4.43 (3.16–6.21) < 0.001 | |
| 40–59 | 43 | 787 | 54.64 | 117 | 10,618 | 11.02 | 4.96 (3.50–7.03) < 0.001 | 4.89 (3.41–7.01) < 0.001 | |
| > 60 | 14 | 226 | 61.95 | 55 | 3214 | 17.11 | 3.62 (2.01–6.51) < 0.001 | 3.50 (1.94–6.34) < 0.001 | |
CI Confidence interval, ICD-9-CM International Classification of Diseases, Ninth revision, clinical modification, IR Incidence rate per 1000 person-years, IRR Incidence rate ratio, n.c. Not calculable, SLE Systemic lupus erythematosus
aAdjusted for age, sex, socioeconomic status, and geographic region