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. Author manuscript; available in PMC: 2021 Jan 7.
Published in final edited form as: Tuberculosis (Edinb). 2020 Jan 7;120:101898. doi: 10.1016/j.tube.2020.101898

Table 2.

Hypothetical performance of different gene signatures to predict progression to TB disease in the Brazil dataset

Gene signature PPV (95% CI) NPV (95% CI)
ACS-COR 0.106 (0.057–0.165) 0.968 (0.946–0.982)
RISK4 0.061 (0.035–0.114) 0.956 (0.933–0.976)
Sweeney 0.080 (0.042,0.136) 0.961 (0.939,0.976)
Jacobsen 0.072 (0.399,0.113) 0.964 (0.938,0.980)
Sambarey 0.073 (0.045,0.116) 0.968 (0.944,0.985)
Kaforou 0.073 (0.046,0.115) 0.970 (0.942,0.985)