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. Author manuscript; available in PMC: 2020 Aug 1.
Published in final edited form as: Appl Microbiol Biotechnol. 2019 Jun 15;103(16):6711–6723. doi: 10.1007/s00253-019-09958-x

Fig. 4.

Fig. 4

Post-treatment administration of antibiotic cocktail eliminates pNAPE-EcN-induced reductions of weight gain, fat gain, and food intake in mice feeding on high fat diet. All values are mean±SEM (n = 6 mice per group). A. Effect of treatments on change in body weight from start of treatment (2way-ANOVA, treatment p < 0.0001, time p<0.0001, Tukey’s multiple comparison test # p<0.05 pNAPE-EcN+no Abx vs Vehicle or pEcN + Abx; *p <0.05 pNAPE-EcN+no Abx vs pEcN+Abx; +p<0.05 pNAPE-EcN+Abx vs Vehicle or pEcN+Abx or pEcN+no Abx; ^ p<0.05 pNAPE-EcN+no Abx vs pNAPE-EcN+ Abx). B. Effect of treatments on change in body fat from start of treatment (2way-ANOVA, treatment p < 0.0001, time p<0.0001; Tukey’s multiple comparison test # p<0.05 pNAPE-EcN+no Abx vs Vehicle or pEcN+no Abx or pEcN + Abx; ^ p<0.05 pNAPE-EcN+no Abx vs pNAPE-EcN+ Abx). C. Effect of treatments on lean body mass (2way-ANOVA, p=0.9349 treatment, time p<0.0001). D. Effect of treatments on cumulative food intake from start of treatment (2way-ANOVA, treatment p<0.0001, time p <0.0001).