Table 3. Clinicopathological characteristics between germline mutation carriers and non-carriers.

Characteristics	Non-carriers		Germline mutation carriers		P-value
Age			0.011*
Median (range)	50 (25-86)			45 (22-72)
<40 years	78	16.74%	18	31.03%
> 40 years	388	83.26%	40	68.97%
Menopausal status					0.013a*
Pre	238	51.07%	42	72.41%
Post	216	46.35%	15	25.86%
Unknown	11	2.36%	1	1.72%
Male	1	0.21%	0	0.00%
Family history of breast or ovarian cancer				<0.001*
Yes	65	13.95%	28	48.28%
No	311	66.74%	19	32.76%
Unknown	90	19.31%	11	18.97%
Tumor size					0.561a
≤2 cm	179	38.41%	20	34.48%
> 2 cm	266	57.08%	37	63.79%
Unknown	21	4.51%	1	1.72%
Lymph nodes status					0.731a
Negative	226	48.50%	30	51.72%
Positive	220	47.21%	27	46.55%
Unknown	20	4.29%	1	1.72%
Grade					0.420a
I	21	4.51%	2	3.45%
II	212	45.49%	22	37.93%
III	202	43.35%	32	55.17%
Unknown	31	6.65%	2	3.45%
Histology					0.973a
DCIS	13	2.79%	1	1.72%
Infiltrating Ductal Carcinoma	404	86.70%	53	91.38%
Infiltrating Lobular Carcinoma	9	1.93%	1	1.72%
Other, specify	21	4.51%	2	3.45%
Unknown	19	4.08%	1	1.72%
ER status					0.733a
Negative	124	26.61%	15	25.86%
Positive	321	68.88%	42	72.41%
Unknown	21	4.51%	1	1.72%