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. 2020 Feb 23;12(4):3647–3661. doi: 10.18632/aging.102835

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Copyright © 2020 Chen et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY 3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

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ENSG00000254041.1 promotes cell cycle and cell proliferation in PC cells. (A) Knockdown of the ENSG00000254041.1 expression decreased the percentage of S-phase and increased G0/G1 phase cell in both of SW1990 and BxPC-3 cells, while overexpression of ENSG00000254041.1 in Panc-1 cells resulted in the opposite effects. (B) Downregulation of ENSG00000254041.1 inhibited proliferation of SW1990 and BxPC-3, while overexpression of ENSG00000254041.1 promoted Panc-1 cells proliferation. Three samples in each group. *p < 0.05, **p < 0.01, ***p < 0.001 compared with si-NC or vector.