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Ligustilide attenuates H2O2-induced and Rotenone-induced mitochondrial impairment in HT22 cells. (A, B) Western blotting was used to detect mitochondrial morphology-related proteins (C, G) Mfn1. (D, H) Mfn2. (E, L) P-Drp1. (F, I) P-AMPK.. Ligustilide 10 (10 mg/kg/d); Ligustilide 20 (20 mg/kg/d). Data represent mean ± SD (n = 20 per group). #p < 0.05, ##p < 0.01, ###p < 0.001 versus SAMR1; *p < 0.05, **p < 0.01, ***p < 0.001 versus SAMP8.
