Table 3. Potential small-molecule drugs identified using the Connectivity Map database.
Rank | Cmap name | Mean | n | Enrichment | P | Specificity | Percent non-null |
1 | camptothecin | -0.727 | 3 | -0.985 | 0 | 0.0568 | 100 |
2 | daunorubicin | -0.661 | 4 | -0.952 | 0 | 0.0088 | 100 |
3 | 0175029-0000 | -0.753 | 6 | -0.952 | 0 | 0 | 100 |
4 | resveratrol | -0.726 | 9 | -0.836 | 0 | 0 | 100 |
5 | trichostatin A | -0.419 | 182 | -0.394 | 0 | 0.3663 | 84 |
6 | GW-8510 | -0.663 | 4 | -0.927 | 0.00002 | 0.0916 | 100 |
7 | colistin | 0.567 | 4 | 0.873 | 0.00036 | 0 | 100 |
8 | dipyridamole | -0.506 | 6 | -0.756 | 0.0004 | 0.0123 | 100 |
9 | fludrocortisone | 0.269 | 8 | 0.669 | 0.00048 | 0.0177 | 50 |
10 | apigenin | -0.619 | 4 | -0.873 | 0.00056 | 0.0163 | 100 |
Note: camp: Connectivity Map.