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. 2020 Feb 18;12(4):3682–3693. doi: 10.18632/aging.102837

Figure 3.

Figure 3

Exosomes from RIC rats significantly promoted cardiac remodeling and angiogenesis after myocardial infarction. (A) Histopathological analysis of heart tissues by HE and Masson (scale bar= 100 μm); (B) Investigation of angiogenesis after RIC exosomes treatment by vWf IHC staining (scale bar= 100 μm); (C) RIC exosomes treatment significantly decreased the infarction ratio; (D) RIC treatment significantly elevated left ventricular ejection fraction; (E) RIC treatment significantly promoted left ventricular fractional shortening. Data were shown as the mean ± SD (n = 3/each group), * P<0.05 compared with respective time point in the control group, # P<0.05 compared with 7 days’ time point in the group RIC exosomes.