Table 3. The prognostic value of different clinical parameters.

	Univariate analysis				Multivariate analysis
	HR	95% CI	P-value		HR	95%CI	P-value
Age	1.02	0.99-1.03	0.154		1.03	1.01-1.05	0.002
Gender	1.02	0.70-1.49	0.909		0.88	0.59-1.31	0.536
Smoking	0.98	0.82-1.17	0.814		1.04	0.87-1.24	0.661
Stage	1.60	1.35-1.89	<0.001		1.50	1.20-1.88	<0.001
T	1.48	1.17-1.88	<0.001		1.08	0.83-1.41	0.551
N	1.44	1.23-1.69	<0.001		1.16	0.94-1.43	0.181
M	1.05	0.85-1.30	0.623		1.11	0.88-1.38	0.375
Risk score	1.21	1.15-1.27	<0.001		1.26	1.19-1.34	<0.001