Table 3. Univariate and multivariate analyses of prognostic factors in 352 cases of glioma (LGG).
| Parameter | Univariate analysis | Multivariate analysis | ||||
| HR | 95% CI | P | HR | 95% CI | P | |
| Age | 1.06 | 1.04-1.07 | <0.001 | 1.05 | 1.04-1.07 | <0.001 |
| New_tumor_event | 4.36 | 2.61-7.30 | <0.001 | 1.54 | 0.85-2.80 | 0.155 |
| Cancer_status | 12.1 | 4.43-33.03 | <0.001 | 4.11 | 1.41-12.00 | 0.010 |
| Grade | 3.18 | 1.98-5.09 | <0.001 | 2.12 | 1.27-3.54 | 0.004 |
| Primary_therapy | 0.41 | 0.31-0.53 | <0.001 | 0.56 | 0.41-0.80 | 0.001 |
| H19 | 2.00 | 1.44-2.78 | <0.001 | 1.54 | 1.09-2.17 | 0.014 |
| Histological_type | 1.41 | 1.10-1.81 | 0.007 | 1.57 | 1.19-2.08 | 0.001 |
| Radiation_therapy | 1.84 | 1.11-3.07 | 0.019 | 0.70 | 0.39-1.25 | 0.226 |
| Targeted_molecular_therapy | 1.33 | 0.86-2.06 | 0.202 | |||
| Laterality | 0.87 | 0.70-1.08 | 0.209 | |||
| Headache_history | 0.77 | 0.49-1.22 | 0.270 | |||
| Motor_movement_changes | 1.32 | 0.80-2.18 | 0.277 | |||
| Seizure_history | 0.86 | 0.56-1.31 | 0.470 | |||
| Sensory_changes | 1.13 | 0.65-1.95 | 0.668 | |||
| Sample_type | 1.10 | 0.50-2.40 | 0.815 | |||
| Gender | 1.02 | 0.67-1.55 | 0.929 | |||
| Mental_status_changes | 1.01 | 0.61-1.69 | 0.966 | |||
| Visual_changes | 1.00 | 0.53-1.88 | 0.992 | |||
LGG: low grade glioma; Bold values indicate P<0.05. HR: hazard ratio; CI: confidence interval.