Table 1. Demographic and clinical characteristics of patients with autosomal dominant polycystic kidney disease (ADPKD) and controls.
| Characteristic | Inpatient patients | P-value | Catastrophic illness patients | P-value | |||
| No. (%) of individuals | No. (%) of individuals | ||||||
| With ADPKD (N=4342) | Control (N=21710) | With ADPKD (N=651) | Control (N=3255) | ||||
| Gender | 0.99 | 0.99 | |||||
| Female | 1946 (44.8) | 9730 (44.8) | 336 (51.6) | 1680 (51.6) | |||
| Male | 2396 (55.2) | 11980 (55.2) | 315 (48.4) | 1575 (48.4) | |||
| Age Group | 0.99 | 0.99 | |||||
| 20-39 | 696 (16.0) | 3480 (16.0) | 190 (29.2) | 950 (29.2) | |||
| 40-59 | 1673 (38.5) | 8365 (38.5) | 350 (53.8) | 1750 (53.8) | |||
| ≥60+ | 1973 (45.5) | 9865 (45.5) | 111 (17.1) | 555 (17.1) | |||
| Mean (SD) | 58.1 (17.2) | 58.0 (17.2) | 0.64 | 47.3 (12.8) | 47.2 (12.9) | 0.86 | |
| Urbanization | 0.0002 | 0.02 | |||||
| Provinces | 1175 (27.1) | 6105 (28.1) | 218 (33.5) | 1042 (32.0) | |||
| Counties | 1399 (32.2) | 6334 (29.2) | 234 (35.9) | 1020 (31.3) | |||
| Districts | 716 (16.5) | 3519 (16.2) | 86 (13.2) | 551 (16.9) | |||
| Urban villages | 1052 (24.2) | 5752 (26.5) | 113 (17.4) | 642 (19.7) | |||
| Geography | 0.003 | <0.0001 | |||||
| North | 1936 (44.6) | 9545 (44.0) | 312 (47.9) | 1553 (47.7) | |||
| Central | 818 (18.8) | 4371 (20.1) | 89 (13.7) | 629 (19.3) | |||
| South | 1298 (29.9) | 6621 (30.5) | 181 (27.8) | 916 (28.1) | |||
| East | 290 (6.68) | 1173 (5.40) | 69 (10.6) | 157 (4.82) | |||
| Income (NTD) | 0.76 | 0.19 | |||||
| <18000 | 1912 (44.0) | 9637 (44.4) | 243 (34.3) | 1339 (41.1) | |||
| 18000-34999 | 1933 (44.5) | 9539 (43.9) | 311 (47.8) | 1468 (45.1) | |||
| ≥35000 | 497 (11.5) | 2534 (11.7) | 97 (14.9) | 448 (13.8) | |||
| Comorbidity | |||||||
| Diabetes | 489 (11.3) | 1114 (5.13) | <0.0001 | 63 (9.69) | 292 (8.97) | 0.57 | |
| Hypertension | 1969 (45.4) | 1999 (9.21) | <0.0001 | 461 (70.8) | 635 (19.5) | <0.0001 | |
| Hyperlipidemia | 233 (5.37) | 393 (1.81) | <0.0001 | 180 (27.7) | 464 (14.3) | <0.0001 | |
| CAD | 548 (12.6) | 1041 (4.80) | <0.0001 | 87 (13.4) | 258 (7.93) | <0.0001 | |
| Atrial fibrillation | 119 (2.74) | 184 (0.85) | <0.0001 | 6 (0.92) | 15 (0.46) | 0.14 | |
| Congestive heart failure | 260 (5.99) | 330 (1.52) | <0.0001 | 22 (3.38) | 36 (1.11) | <0.0001 | |
| Obesity | 5 (0.12) | 4 (0.02) | 0.009 | 0 (0.00) | 4 (0.12) | 0.99 | |
| Gouty arthritis | 247 (5.69) | 235 (1.08) | <0.0001 | 74 (11.4) | 107 (3.29) | <0.0001 | |
| Medications | |||||||
| ACE-Is | 207 (31.8) | 331 (10.2) | <0.0001 | ||||
| ARBs | 392 (60.2) | 405 (12.4) | <0.0001 | ||||
| Statins | 159 (24.4) | 393 (12.1) | <0.0001 | ||||
| Allopurinol | 71 (10.9) | 48 (1.47) | <0.0001 | ||||
| Pentoxifylline | 113 (17.4) | 92 (2.83) | <0.0001 | ||||
Chi-square test and t-test; CAD, coronary artery disease; SD, standard deviation; Medicine users were defined during the study period