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. 2020 Feb 20;12(4):3694–3712. doi: 10.18632/aging.102841

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Copyright © 2020 Lin et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY 3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

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Validation of hub genes and PPI map construction. (A) Relationship between 10 hub genes expression and CD8⁺ T cell infiltration level; P < 0.05 is considered statistically significant. (B) Scatter plot of CCL5 expression and CD8⁺ T cell infiltration level. (C) The heat map shows the correlation between the ten identified hub genes and the TIICs from the TISIDB database. The redder color indicates a higher correlation, and greener color indicates a lower correlation. (D) Protein-protein interaction map of the ccRCC immune microenvironment.