Fillmann 1995.

Methods	Randomisation: no details. Blinding: double‐blind (orange juice for the control group; no details about blinding the surgeons). Withdrawals/dropouts: no withdrawals or dropouts. Follow up: 30 days after surgery.
Participants	Inclusion criteria: participants admitted for elective colorectal surgery with primary anastomosis. Exclusion criteria: no exclusions. Diseases (Group A/B): colorectal cancer (22/21); diverticular disease (5/6); inflammatory bowel disease (2/3); ischemics colitis (1/0). Number: 60 (33 male; 27 female). Age: 31‐82 years. Location: Porto Alegre, RS, Brazil. Date: 1992‐1993. Antibiotics: metronidazole + gentamicin 1 h before surgery, and then for 48 h.
Interventions	Group A ‐ MBP (n = 30): 500 ml mannitol 20% + 500 ml orange juice. Group B ‐ orange juice (n = 30).
Outcomes	Wound infection: Group A = 1; Group B = 2. Peritonitis: Group A = 2; Group B = 1. Extra‐abdominal complications (non‐infectious): ‐Mechanical obstruction: Group A = 0; Group B = 1. ‐Dehiscence of wall suture: Group A = 0; Group B = 1. ‐Pulmonary embolism: Group A = 1; Group B = 0. Extra‐abdominal complications (infections): ‐Pneumonia: Group A = 1; Group B = 1. ‐Urinary infection: Group A = 1; Group B = 2.
Notes	The sample size was calculated, but no details given. Included participants without anastomosis. Recurrence was not mentioned. No deaths in this trial.
Risk of bias
Bias	Authors' judgement	Support for judgement
Allocation concealment (selection bias)	Low risk	A ‐ Adequate