| Methods |
Randomisation: Central randomisation; random numbers.
Blinding: none. |
| Participants |
Inclusion criteria: participants undergoing elective open surgery for cancer, adenoma or diverticular disease of the rectum, involving an anastomosis; aged between 18‐85 years with an ASA grade of I, II or III.
Exclusion criteria: laparoscopic surgery; procedures involving a stoma; ASA scope IV and a life expectancy of less than 6 months.
Diseases: cancer, adenomas, diverticular disease.
Number: 44.
Date: January 1999‐March 2005.
Antibiotics: oral sulphamethoxazole‐trimethoprim + metronidazole, cephalosporin + metronidazole, or doxycycline + metronidazole. |
| Interventions |
Group A ‐ MBP (n = 27): PEG or sodium phosphate.
Group B ‐ no preparation (n = 17). |
| Outcomes |
Anastomotic dehiscence: Group A = 3, Group B = 0.
Wound infection: Group A = 4, Group B = 1.
General infections: Group A = 5, Group B = 1. |
| Notes |
A multicenter study.
Surgeons in this study were all specialists in colorectal surgery.
Intention‐to‐treat analysis.
This is a group of participants, who were first included in Jung 2007, but later excluded due to rectal surgery. These data are unpublished thus far. |
| Risk of bias |
| Bias |
Authors' judgement |
Support for judgement |
| Allocation concealment (selection bias) |
Low risk |
A ‐ Adequate |
