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Representative immune-labeled cross sections of tumors treated with phosphate buffer saline (A-C) and prodrug nanoparticles (D-F). Sections were incubated with pSTAT-3 antibody (red) and background protein β-actin (green) around cell nuclei stained with DAPI (blue) to show significantly high level of pSTAT-3 in phosphate buffer saline treated tumors compared to treated with Pro-nifuroxazide nanoparticles.
