Figure 1. Flowchart for the diagnostic imaging workup of patients suspected of infective endocarditis.[176] FDG: Fluorodeoxyglucose; PET: Positron emission tomography; MDCTA: Electrocardiogram-gated multidetector CT angiography. TTE: Transthoracic echocardiogram; TEE: Transesophageal echocardiogram. Circles indicate the end of a diagnostic pathway, when efforts to diagnose (extracardiac complications of) infective endocarditis can be ceased; * Allocation specifically for the detection of extracardiac foci.