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. 2020 Mar 9;8:e8731. doi: 10.7717/peerj.8731

Table 3. Functional roles of 10 hub genes.

Genes symbol Full name Function
MAD2L1 Mitotic arrest deficient 2 like 1 Preventing the onset of anaphase
POLQ DNA polymerase θ Alternative nonhomologous end joining
HELLS Helicase, lymphoid specific DNA strand separation
ANLN Aniline actin binding protein Cell growth and migration
BIRC5 Bucovina IAP repeat containing 5 Preventing apoptotic cell death
ATAD2 ATPase family AAA domain containing 2 Chaperone-like functions
CCNB2 Cyclin B2 The cell cycle regulatory machinery
PTK2 Protein tyrosine kinase 2 Cytoplasmic protein tyrosine kinase
ICAM1 Intercellular adhesion molecule 1 Endothelial cells and cells of the immune system
ITGAX Integrin subunit alpha X Encoding the integrin alpha X chain protein