TABLE 1.
Baseline Demographic and Clinical Characteristics of Study Participants in the TELEmedicine for Inflammatory Bowel Disease (TELE-IBD) Trial
| Characteristics | Standard of Care (n = 72) | TELE-IBD W (n = 71) | TELE-IBD EOW (n = 74) | P-Value |
|---|---|---|---|---|
| Mean age (± SD) | 39.5 (12.0) | 37.3 (11.6) | 39.3 (13.4) | 0.49 |
| Sex, n (%) | ||||
| Female | 45 (62.5) | 39 (55.0) | 44 (59.5) | 0.65 |
| Race, n (%) | ||||
| White | 66 (91.7) | 67 (94.4) | 71 (96.0) | 0.54 |
| Study site, n (%) | 0.72 | |||
| University of Maryland | 37 (51.4) | 39 (54.9) | 43 (58.1) | |
| University of Pittsburgh | 23 (31.9) | 25 (35.2) | 21 (28.4) | |
| Vanderbilt University | 12 (16.7) | 7 (9.9) | 10 (13.5) | |
| Tobacco use | 0.67 | |||
| Never smoked | 46 (65.7) | 45 (66.2) | 41 (56.2) | |
| Former smoker | 17 (24.3) | 17 (25.0) | 25 (34.2) | |
| Current smoker | 7 (10.0) | 6 (8.8) | 7 (9.6) | |
| Disease type, n (%) | 0.36 | |||
| Crohn’s disease | 50 (69.4) | 45 (63.4) | 55 (74.3) | |
| Ulcerative colitis | 22 (30.6) | 26 (36.6) | 19 (25.7) | |
| UC disease extent, n (%) | 0.99 | |||
| Extensive | 15 (68.2) | 18 (69.2) | 13 (68.4) | |
| CD disease location, n (%) | ||||
| Ileal | 9 (18.0) | 8 (17.8) | 11 (20.0) | 0.95 |
| Colonic | 12 (24.0) | 10 (22.2) | 6 (10.9) | 0.17 |
| Ileocolonic | 22 (44.0) | 25 (55.6) | 26 (47.3) | 0.51 |
| Upper tract involvement | 5 (10.0) | 5 (11.1) | 7 (12.7) | 0.91 |
| CD disease behavior, n (%) | ||||
| Inflammatory | 25 (50.0) | 18 (40.0) | 17 (33.3) | 0.23 |
| Obstructing | 10 (20.0) | 9 (20.0) | 13 (25.5) | 0.75 |
| Perforating | 15 (30.0) | 18 (40.0) | 21 (41.2) | 0.45 |
| Perianal disease, n (%) | 15 (29.4) | 12 (27.9) | 15 (27.8) | 0.97 |
| Age at disease onset in years, mean (± SD) | 26.8 (11.2) | 25.4 (10.9) | 27.5 (12.1) | 0.56 |
| Disease duration in years, mean (± SD) | 12.4 (9.8) | 11.8 (8.6) | 11.7 (9.4) | 0.91 |
| Time since last flare in years, mean (± SD) | 0.6 (0.7) | 0.7 (0.6) | 0.6 (0.6) | 0.72 |
| Disease activity scores mean (± SD) | ||||
| HBI | 4.4 (4.0) | 3.1 (3.1) | 4.3 (3.9) | 0.15 |
| SCCAI | 3.0 (3.1) | 2.7 (2.6) | 2.3 (2.8) | 0.71 |
| IBDQ score, mean (± SD) | 168.1 (32.5) | 173.2 (32.5) | 174.9 (33.5) | 0.43 |
| CRP of 3 or greater | 20 (35.7) | 25 (41.7) | 23 (35.4) | 0.72 |
SD = Standard deviation; HBI = Harvey Bradshaw Index; SCCAI = Simple Clinical Colitis Activity Index; PCS = Physical Component Score; MCS = Mental Component Score; CRP = C-reactive protein; IBDQ = Inflammatory Bowel Disease Questionnaire; W = weekly; EOW = every other week.