Table 1. Optimized radiolabeling parameters and quality control of 99mTc-PSMA-11.
Radiolabeling parameters | |
Precursor amount | 50 μg |
Stannous chloride | 40 μg |
pH | 5 |
Heating | 90 °C, 15 min |
Quality control | |
Radiochemical yield (TLC) | 60 ± 5% (n = 10) |
Radiochemical purity (HPLC) | |
Sep pak purification | 92 ± 1% |
Filtration | 98 ± 1% |