Fig 2. Adjusted* percent change in risk of death per year among IS patients by subtype, ethnic, sex, and age groups.

Adjusted risk ratios were determined with multivariate Cox models evaluating calendar year as a continuous variable. *Adjusted for demography, prior risk factors, stroke severity, and processes of care as appropriate (see Table A, Table B, and Table C in S1 Appendix for all model covariates). Full parameter estimates are available in Table A, Table B, and Table C in S1 Appendix. CE, cardio-embolism; IS, ischaemic stroke; LAA, large-artery atherosclerosis; SVO, small-vessel occlusion; UND, undetermined aetiologies.