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. 2020 Mar 12;18(3):e3000657. doi: 10.1371/journal.pbio.3000657

Fig 8. Microtubule nucleation is required for normal dendrite regeneration.

Fig 8

(A) Representative images of ddaE dendrite regeneration in control, ɣTub, and plp RNAi neurons. (B) Number of branch points added 24 HPD is shown. (C) Representative ddaC arbors 24 HPD expressing RNAi hairpins targeting plp and γTub. (D) Quantitation of ddaC dendrite regeneration diameter 24 HPD is shown. (E) Example images of ddaE axon regeneration in Plp RNAi neurons are shown. (F) Mean normalized regeneration length (μm) is shown in the graph. Note: axon regeneration control data set is repeated (F) from Fig 5 for comparison. Error bars are standard deviation; sample size (within bar, bottom) represents individual animals/neurons. Mann–Whitney U test, *P < 0.05, **P < 0.01, ***P <0.001. Quantitation is contained in S1 Data. da, dendritic arborization; ddaC/E, dorsal da C/E; HPA, hours postaxotomy; HPD, hours postdendrotomy; plp, pericentrin-like protein; RNAi, RNA interference; γTub, γTubulin.