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The graphs show the numerical solutions of the indicated variables under the reference parameters as in Figs 4 and 6. The normal resting state is perturbed (in the absence of SAP, S = 0 nM) by setting the membrane potential to a higher value (V = 0 mV) at time t = 0 for a short period of 0.25 s (indicated by the two vertical dashed lines).
